KMID : 0371320070720020128
|
|
Journal of the Korean Surgical Society 2007 Volume.72 No. 2 p.128 ~ p.132
|
|
Single Institutional Experiences of Insulinoma
|
|
Lee Sun-Hyuck
Kang Chang-Moo Kim Jun-Young Choi Gi-Hong Kim Kyung-Sik Choi Jin-Sub Lee Woo-Jung Kim Byong-Ro
|
|
Abstract
|
|
|
Purpose: We present our experiences of pancreatic insulinoma among the functioning neuroendocrine neoplasm of the pancreas, to review the natural history and suggest proper management.
Methods: From June 1990 to August 2006, patients with diagnosis of pancreatic insulinoma were retrospectively reviewed.
Results: Thirteen patients (5 men and 8 women) with median age of 42 years (range, 12¡68 years) were investigated. One patient (12%) with pancreatic insulinoma was MEN 1. Intraoperative ultrasound scan (sensitivity, 88%) was the most powerful modality for tumor localization. Sixteen neoplasms with median tumor size 1 cm (range, 0¡3 cm) were found. Ten neoplasm (62%) were located in the heads/ necks of the pancreas. Six neoplasm (38%) were located in the tails. Five neoplasm (31%) were located around the neck areas near the SMV or PV. Twelve patients (92%) underwent enucleation, and two patients (15%) underwent distal pancreatectomy with splenectomy. 100% of patients with pancreatic insulinoma have survived and the overall disease free 10-year survival was found to be about 85.7%.
Conclusion: Exact localization of tumor by intraoperative ultrasound and effective surgical removal can be significantly beneficial for good prognosis. (J Korean Surg Soc 2007; 72:128-132)
|
|
KEYWORD
|
|
Neuroendocrine neoplasm, Pancreas, Insulinoma
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|